With click-to-dial you can mouse-click any number from your phone book and get instantly connected.
If you want to call another number, all you have to do is click their number in your phone book and YOUR phone will ring, pick it up, and wait to be connected. It's that easy.
Click to dial is also perfect for calling users on other VOIP networks which may only be reachable with a sip uri(a sip uri is like an email address, except it points to a VOIP phone) that can't be dialed from a regular phone keypad.